
簡要描述:Recombinant Human FGF-12 ProteinRecombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.
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Product Category詳細(xì)介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號 | abs04191 | 規(guī)格 | 10ug |
| 供貨周期 | 現(xiàn)貨 | 主要用途 | is produced by our E.coli expression sys |
| 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Recombinant Human FGF-12 Protein
| 產(chǎn)品描述 | |
| 描述 | Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed. |
| 別名 | FGF-12蛋白;Fibroblast Growth Factor 12; FGF-12; Fibroblast Growth Factor Homologous Factor 1; FHF-1; Myocyte-Activating Factor; FGF12; FGF12B; FHF1 |
| 種屬 | Human |
| 來源 | Escherichia coli. |
| 形態(tài) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.5. |
| 儲存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 性能 | |
| 序列 | MESKEPQLKGIVTRLFSQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQESGRAWFLGLNKEGQIMKGNRVKKT KPSSHFVPKPIEVCMYREQSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST |
| 標(biāo)簽 | No Tag |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內(nèi)毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 活性 | Immobilized Human FGF-12 at 2ug/ml (100 μl/well) can bind Human FGFR3-Fc . The ED50 of Human FGF-12 is 0.5-4 ug/ml . |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 靶標(biāo) | |
| 背景說明 | Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Accession | P61328 |
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | CardiovascularAngiogenesisGrowth FactorsFGFFGF Signal TransductionGrowth Factors/HormonesFGF |
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