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詳細介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號 | abs04246 | 規格 | 10ug |
| 供貨周期 | 現貨 | 主要用途 | is produced by our Mammalian expression |
| 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Recombinant Human TNFRSF6 Protein(C-6His)
| 產品描述 | |
| 描述 | Recombinant Human Fas is produced by our Mammalian expression system and the target gene encoding Gln26-Asn173 is expressed with a 6His tag at the C-terminus. |
| 別名 | Fas蛋白；TNFRSF6蛋白；CD95蛋白;Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; APT1; FAS1; TNFRSF6; FAS; CD95 |
| 種屬 | Human |
| 來源 | Human Cells |
| 形態 | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH 7.4. |
| 儲存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 性能 | |
| 序列 | QVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKE YTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIK ECTLTSNTKCKEEGSRSNVDHHHHHH |
| 標簽 | C-6His |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 靶標 | |
| 背景說明 | FAS is a receptor and contains three TNFR-Cys repeats and one death domain. It has been shown that FAS is involved in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. FADD (adapter molecule) recruits caspase-8 to the activated receptor, the resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. FAS-mediated apoptosis may play a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
| Accession | P25445 |
| 研究領域 | |
| 研究領域 | ApoptosisReceptorsDeath Receptors ImmunologyCell Type MarkersCDCytokines ImmunologyInnate ImmunityCytokinesTNF Superfamily |
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