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簡(jiǎn)要描述：Recombinant Human IL-17RA Protein(C-Fc)is produced by our Mammalian expression system and the target gene encoding Leu33-Trp320 is expressed with a Fc tag at the C-terminus.
產(chǎn)品型號(hào)：abs04089廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2026-04-07訪 問(wèn) 量：1446產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | 純度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 貨號(hào) | abs04089 | 規(guī)格 | 10ug |
| 供貨周期 | 現(xiàn)貨 | 主要用途 | is produced by our Mammalian expression |
| 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Recombinant Human IL-17RA Protein(C-Fc)
| 產(chǎn)品描述 | |
| 描述 | Recombinant Human Interleukin-17 receptor A is produced by our Mammalian expression system and the target gene encoding Leu33-Trp320 is expressed with a Fc tag at the C-terminus. |
| 別名 | IL-17 Receptor A蛋白；IL-17RA蛋白；CD217蛋白;Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD_antigen; CD217; IL17RA; IL17R |
| 種屬 | Human |
| 來(lái)源 | Human Cells |
| 形態(tài) | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 儲(chǔ)存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 性能 | |
| 序列 | LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIE WTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVH HLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNES THYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQ |
| 標(biāo)簽 | C-Fc |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 內(nèi)毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 活性 | Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells.The ED50 for this effect is 20-100 ng/ml. |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 靶標(biāo) | |
| 背景說(shuō)明 | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. |
| Accession | Q96F46 |
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | ImmunologyInnate ImmunityMacrophage / Inflamm. ImmunologyInnate ImmunityCytokinesInterleukins |
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