產品分類
Product Category詳細介紹
| 品牌 | absin | CAS | 67-45-8 |
|---|---|---|---|
| 分子式 | C8H7N3O5 | 純度 | 99% |
| 分子量 | 225.16 | 貨號 | abs47027283 |
| 規格 | 50mg | 供貨周期 | 現貨 |
| 主要用途 | is a nitrofuran derivative with antiprot | 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Furazolidone 67-45-8
| 產品描述 | |
| 描述 | Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. |
| 純度 | 99% |
| 儲存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 呋喃zuo酮 |
| 外觀 | 淡黃色結晶性粉末 |
| 可溶性/溶解性 | DMSO > 10 mM |
| 生物活性 | |
| In vitro(體外研究) | Furazolidone displays potent antiproliferative properties at submicromolar concentrations and induces apoptosis in AML cell lines. Furazolidone treatment of certain AML cells induces myeloid cell differentiation by morphology and flow cytometry for CD11b expression, resulting in increased stability of tumor suppressor p53 protein in AML cells. |
| In vivo(體內研究) | FZ accelerates its own metabolism in the chicken by induction of the activity of CPR whereas no effect is observed in the rat. |
| 參考文獻 | |
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| 研究領域 | |
| 研究領域 | CancerTumor immunology MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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