全國服務咨詢熱線：
18860915427
18860915427
產品分類
Product Category詳細介紹
| 品牌 | absin | CAS | 58-28-6 |
|---|---|---|---|
| 分子式 | C18H23ClN2 | 純度 | ＞98% |
| 分子量 | 302.84 | 貨號 | abs47027434 |
| 規格 | 100mg | 供貨周期 | 現貨 |
| 主要用途 | is the hydrochloride salt | 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Desipramine hydrochloride 58-28-6
| 產品描述 | |
| 描述 | Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically. |
| 純度 | ＞98% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 鹽酸去甲咪嗪 |
| 外觀 | white to off-white powder |
| 可溶性/溶解性 | DMSO : 83.3 mg/mL (275.06 mM; Need ultrasonic and warming) |
| 生物活性 | |
| 靶點 | 5-HT Receptor |
| In vivo(體內研究) | Treatment of rats with Desipramine hydrochloride for 14 days reduces norepinephrine transporter (NET) expression in a dose-dependent manner, as indicated by a reduction of the specific binding of 3H-nisoxetine to the NET in preparations of cerebral cortex (F(3,16)=4.33, p(3,16)=4.34, p. |
| 參考文獻 | |
| 參考文獻 |
|
| 研究領域 | |
| 研究領域 | MetabolismTypes of diseaseObesity NeuroscienceProcesses NeuroscienceNeurology processMetabolism NeuroscienceNeurotransmissionReceptors / ChannelsGPCRSerotonin Receptors Signal TransductionSignaling PathwayG Protein SignalingGPCR Drug DiscoverySmall Molecule DrugLead Compound Discovery |
產品咨詢
電話
微信掃一掃
地址：上海市浦東新區新浩路58號申江科創園18棟
郵箱：fengmj@univ-bio.com
傳真：