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Product Category詳細介紹
| 品牌 | absin | CAS | 69308-37-8 |
|---|---|---|---|
| 分子式 | C10H12ClNO2 | 純度 | ＞98% |
| 分子量 | 213.66 | 貨號 | abs47028346 |
| 規格 | 5mg | 供貨周期 | 現貨 |
| 主要用途 | a derivative of gamma-aminobutyric acid | 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
(R)-baclofen 69308-37-8
| 產品描述 | |
| 描述 | (R)-baclofena， a derivative of gamma-aminobutyric acid，is commonly utilized for the treatment of spasticity. |
| 純度 | ＞98% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | (R)-ba氯芬；STX209 |
| 外觀 | 白色粉末 |
| 可溶性/溶解性 | water : 4.3 mg/mL (20 mM), with gentle warming |
| 生物活性 | |
| 靶點 | GABAB receptor |
| In vitro(體外研究) | Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(?)-enantiomer is about 100 times more active than the S-(+)-enantiomer. |
| 參考文獻 | |
| 參考文獻 |
| 研究領域 | |
| 研究領域 | Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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