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| 品牌 | absin | CAS | 164204-38-0；119942-99-3 |
|---|---|---|---|
| 分子式 | C23H34N3Na2O10P | 純度 | 98% |
| 分子量 | 588.48 | 貨號 | abs47028406 |
| 規格 | 5mg | 供貨周期 | 現貨 |
| 主要用途 | used as a biochemical tool. | 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
Phosphoramidon Disodium Salt 164204-38-0；119942-99-3
| 產品描述 | |
| 描述 | Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. |
| 純度 | 98% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | DMSO :100 mg/mL (169.92 mM) |
| 生物活性 | |
| 靶點 | metalloendopeptidase |
| In vitro(體外研究) | Phosphoramidon is a powerful inhibitor of thermolysin without inhibiting the other endopeptidases such as trypsin, papain, chymotrypsin. Phosphoramidon reduces tumor cell invasion in CC531 cells. |
| In vivo(體內研究) | In rats bearing colon carcinoma CC531 xenografts, Phosphoramidon (250 mg/Rat i.p.) significantly reduces tumor cell growth. Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice, and thus can be use to model Alzheimer's disease (AD). |
| 參考文獻 | |
| 參考文獻 |
| 研究領域 | |
| 研究領域 | NeuroscienceEndocrine system Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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