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| 品牌 | absin | CAS | 55778-02-4 |
|---|---|---|---|
| 分子式 | C18H18N4 | 純度 | 98% min |
| 分子量 | 290.36 | 貨號 | abs812232 |
| 規格 | 5mg | 供貨周期 | 現貨 |
| 主要用途 | is a novel small molecular and potency C | 應用領域 | 化工,生物產業,農林牧漁,制藥/生物制藥,綜合 |
WZ811 55778-02-4
| 產品描述 | |
| 描述 | WZ811 is a novel small molecular and potency CXCR4 antagonist with EC50 of 0.3 nM. |
| 純度 | 98% min |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | WZ-811; WZ 811 |
| 可溶性/溶解性 | DMSO Solubility: 30 mg/mL (103.32 mM) |
| 生物活性 | |
| 靶點 | CXCR4 |
| In vitro(體外研究) | WZ811 is a highly potent competitive antagonist of CXCR4. WZ811 is effective in counteracting SDF-1 on cAMP reduction at doses as low as a few nanomoles. WZ811 blocks SDF-1-mediated invasion with EC50 of 5.2 nM. |
| 研究領域 | |
| 研究領域 | CancerCancer MetabolismResponse to hypoxia ImmunologyAdaptive ImmunityRegulatory T Cells ImmunologyImmune System DiseasesAntiviral SignalingHIV-related ImmunologyInnate ImmunityChemokinesAlpha Chemokine Rec. (CXCR) MetabolismPathways and ProcessesMetabolism processesHypoxia MicrobiologyInterspecies InteractionHost Virus Interaction MicrobiologyOrganismVirusDNA VirusssRNA positive strand virusSARS Coronavirus NeuroscienceDevelopment NeuroscienceNeurology processGrowth and DevelopmentAxonal Guidance Proteins Stem CellsEndothelial ProgenitorsEndothelial Markers Stem CellsHematopoietic ProgenitorsSurface Molecules Stem CellsNeural Stem CellsSurface Molecules Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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